Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Ramayyappa, M.
- Evaluation of Anti-bacterial and Anti-inflammatory Activities of Ethanolic Extract of Hibiscus hirtus Linn. Leaves
Abstract Views :59 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
2 Dept. of Pharmacology, Brilliant Group of Institutions, Abdullapaur, R.R. Dist., Hyderabad, Telangana, IN
3 Department of Analysis, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
4 Vijaya Teja Degree College, Addanki, Andhra Pradesh, IN
1 Department of Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
2 Dept. of Pharmacology, Brilliant Group of Institutions, Abdullapaur, R.R. Dist., Hyderabad, Telangana, IN
3 Department of Analysis, A.K.R.G. College of Pharmacy, Nallajerla, Andhra Pradesh, IN
4 Vijaya Teja Degree College, Addanki, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 1 (2022), Pagination: 5 - 10Abstract
The current investigation is started to find the antibacterial and anti-inflammatory activities of the sub shrub Hibiscus hirtus L. The leaves of this conventional shrub were found to possess' different activities which incorporate antibacterial and hostile to helminthic effects. Thus we made an endeavor to perform extraction utilizing ethanol as solvent and soxhlation as a strategy for extraction. The leaves were priorly researched for their pharmacognostic, phytochemical and physical parameters. The antibacterial action of the ethanolic leaf extract was conveyed at various concentrations on strains of gram positive and gram-negative bacteria, for example, Staphylococcus aureus and Escherechia coli individually by utilizing cup and plate technique. The outcomes were outfitted as the zone of inbition acquired around every grouping of the concentrate and were compared with those of standard antibiotic utilized in the analysis, amoxycillin. Anti-inflammatory activity of Hibiscus hirtus L was studied and compared with standard drug, ibuprofen. Ethanollic concentrate of leaves (2.5- 15 mg/ml) and ibuprofen (2.5-15 mg/ml) were utilized to measure the paw edema by plethysmometer and compared with control groups. Hibiscus hirtus L showed critical decrease of paw edema in the chosen model of inflammation for example formalin prompted chronic model of inflammation. Ethanollic concentrate of the plant leaves showed anti- microbial and anti-inflammatory impacts.
Keywords
Hibiscus hirtus L, Anti-inflammatory, Antimicrobial activity, Extraction
References
- Ahameethunisa A.R., Hopper W. Antibacterial activity of Artemisia nilagirica leaf extracts against clinical and phytopathogenic bacteria BMC Comple. Alt. Med. 2010; 10:6.
- Al Farug A., Ibrahim M., Mahmood A., Chowdhury M., Rashid R.B., Kuddus R., Rashid M.A. Pharmacological and phytochemical screenings of ethanol extract of Leeamacrophylla Roxb. Innov. Pharm Pharmacother. 2014;2: 321–327.
- Anosike C.A., Obidoa O., Ezeanyika L.U. Membrane stabilization as a mechanism of the anti-inflammatory activity of methanol extract of garden egg (Solanum aethiopicum) DARU J. Pharmaceut. Sci. 2012; 20(1): 76.
- Arokiyaraj S., Sripriya N., Bhagya R., Radhika B., Prameela L. Phytochemical screening, antibacterial and free radical scavenging effects of Artemisa nilagirica. Mimosa pudica and Clerodendrum siphonanthus – An in vitro study. Asian Pacific J. Tropic. Biomed. 2012;29: S601–S604.
- Avula B., Wang Y.H., Smillie T.J., Mabusela W., Vincent L., Weitz F., Khan I.A. Quantitative determination of flavonoids by column high-performance liquid chromatography with mass spectrometry and ultraviolet absorption detection in Artemisia afar and comparative studies with various species of Artemisia plants. J. AOAC Int. 2009;92: 633–644.
- Banerji A., Luthriya D.L., Kokate S.D. Toxicity of capillin, the insecticidal principle of Artemisia nilagirica Clarke. Indian J. Exp. Biol. 1990;28: 588–589.
- Blaszyle M., Holley R.A. Interaction of monolaurin, eugenol and sodium citrate on growth of common meat spoilage and pathogenic organisms. Int. J. Food Microbial. 1998;39: 175–183.
- Nathan C. Points of control in inflammation. Nature. 2002;420:846-52. 9. Gouwy M, Struyf S, Proost P, Van Damme J. Synergy in cytokine and chemokine network amplifies the inflammatory response. Cytokine Growth Factor Rev. 2005;16: 561-80.
- Wellen KE, Hotamisligil GS. Inflammation, stress and diabetes. J. Clin. Invest. 2005;115: 1111-9.
- Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis and therapeutic opportunities. Inflamm. Bowel Dis. 2006; 12:3-9.
- Whicher J, Chambers R. Mechanisms in chronic inflammation. Immunol. Today. 1984;5: 3-4.
- Vinay K, Abdul KA, Nelson F, Aster JC. Robbins and Cotran’s Pathologic basis of diseases. 8th ed Philadelphia: Elsevier Publishers; 2010: 43-77.
- Laurence LB , Bruce AC, Bjorn CK. Goodman and Gilman's The pharmacological basis of therapeutics.12th ed China: McGraw-Hill Publishers; 2011.
- Eisenberg DM, Kessler RC and Foster C. 1993. Unconventional Medicine in the United States: Prevalence, Costs and Patterns of Use. N Eng J Med. 328:246-52.
- Rakh MS and Chaudhari SR. Evaluation of CNS depressant activity of Momordicadioica Roxb wild fruit pulp. Int. J. Pharm. Pharm. Sci. 2010;2(4):124-6.
- Perry JM. Medicinal plants of East and Southeast Asia: attributed properties and Uses. MIT Press, Cambridge, MA. 1980;334-60. 18. Mahadevan N, Shivali and Kamboj P, Hibiscus sabdariffa L.-An Overview. Natural Product Radiance. 2009;8(1):77-83.
- Alviano DS, Alviano CS. Plant extracts: search for new alternatives to treat microbial diseases. Curr Pharm Biotechnol, Jan, 2009; 10(1): 106–121.
- Malini M, Abirami G, Hemalatha V, Annadurai G. Antimicrobial activity of ethanolic and aqueous ex-tracts of medicinal plants against waste water pathogens. Int J Res Pure Appl Microbiol. 2013; 3(2): 40–42.
- Zhang R, Eggleston K, Rotimi V, Zeckhauser RJ. Antibiotic resistance as a global threat: evidence from China, Kuwait and the United States. Global Health, Apr 7, 2006; 2: 6.
- Dorman HJ, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. 2000; 88(2): 308–316.
- Talib WH, Mahasneh AM. Antimicrobial, cytotoxicity and phytochemical screening of Jordanian plants used in traditional medicine. Molecules. 2010; 15(3): 1811–1824.
- Cruz MC, Santos PO, Barbosa Jr AM, de Melo DL, Alviano CS, Antoniolli AR, Alviano DS, Trindade RC. Antifungal activity of Brazilian medicinal plants involved in popular treatment of mycoses. J Ethnopharmacol. 2007; 111(2): 409–412.
- Antimicrobial activity of ethanolic extracts from some medicinal plants. Australian Journal of Basic and Applied Sciences. 2011; 5(11): 678-683.
- Evaluation of antimicrobial activity of various medicinal plants extracts of Latur zone against pathogens. International Journal of Life Sciences and Resource. 2016; 2(5): 612-618.
- Antimicrobial activity of ethanolic extracts from some medicinal plants. Australian Journal of Basic and Applied Sciences. 2011; 5(11): 678-683.
- M. Hemalatha, B. Arirudran, A. Thenmozhi, U.S. Mahadeva Rao. Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.). Asian J. Pharm. Res. 2011; 1(4): 102- 107.
- Preeti Tiwari. Antimicrobial Activity of Amritarishta Prepared by Traditional and Modern Methods. Asian J. Pharm. Res. 2014; 4(2): 114-116.
- A. Sureka, C. Mary Sharmila, R. Chithra Devi, N. J. Muthu Kumar, V. Banumathi. Evaluation of In Vitro Anti-Inflammatory activity of Kusta Gaja Kesari - A Siddha Herbo Mineral Formulation against Albumin Protein Denaturation. Asian J. Pharm. Res. 2018; 8(3): 145-147.
- Keerti Shrivastava, Sherendra Sahu, Skand K. Mishra, Kantishree De. In vitro Antimicrobial Activity and Phytochemical Screening of Syzygium aromaticum. Asian J. Res. Pharm. Sci. 2014; 4(1): 12-15.
- Preeti Tiwari. Antimicrobial Activity of Ashwagandharishta Prepared by Traditional and Modern Methods. Asian J. Res. Pharm. Sci. 201; 4(3): 115-117.
- Nidhi Rao, Sandhya Mittal, Sudhanshu, Ekta Menghani. Assessment of Phytochemical Screening, Antioxidant and Antibacterial Potential of the Methanolic Extract of Ricinus communis L. Asian J. Pharm. Tech. 2013; 3(1): 20-25.
- Punasiya Rakesh, Pillai Sujit, Yadav Janeshwer. Isolation and identification of compounds from the leaves extract of Hibiscus syriacus L. Asian J. Pharm. Tech. 2015; 5(1): 8-12.
- Merlin NJ, Parthasarathy V, Manavalan R, Devi P, Meera R. Phyto-Physico chemical evaluation, Anti-Inflammatory and Anti microbial activities of Aerial parts of Gmelina asiatica. Asian J. Research Chem. 2009; 2(1): 76-82.
- Swapnali Mohite, Rutuja Shah, Naziya Patel. Antimicrobial Activity of Leaves extracts of Cassia tora. Res. J. Pharma. Dosage Forms and Tech. 2018; 10(1): 10-12.
- R. Suresh, D. Benito Johnson, Appalaraju Gorle, Ashok Kumar Javvadi, Tamil Selvan A. The Wound healing, anti inflammatory and haemostatic effect of Eupatorium odoratum. Research J. Pharmacognosy and Phytochemistry. 2012; 4(2): 75-79..